Protective effects of resveratrol on kidney function tests and renal histopathology in carbon tetrachloride-induced renal toxicity in rats

In this study, it was aimed to investigate the protective effect of Resveratrol, which has a strong antioxidant on kidney tissues rats experimentally induced with carbon tetrachloride nephrotoxicity, by function tests and histopathology. For purpose, 32 male Wistar Albino were used. The subjects randomly selected, 1st group control, 2nd CCl4, 3rd Resveratrol. 4th divided into 4 groups as CCl4 + At end experiment, animals sacrificed under anesthesia samples taken in 10% formalin solution for histopathological analysis. examination, found that control Resveratrol had normal histological structure. CCI4 group, severe hydropic degeneration tubules epithelium, mild coagulation necrosis epithelium hyperemia vessels observed. When examined examined, observed they appearance. As result, determined damage caused CCI4.